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The most effective cerebral protection protocol integrates three components: (1) preoperative cerebrovascular reserve assessment, (2) intraoperative NIRS monitoring with protocolized interventions, and (3) maintenance of cerebral perfusion pressure through goal-directed fluid and vasopressor management (74)

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Do not rub or massage the treated area Post-Treatment Timeline: From Day One to Final Results Immediately After: Mild soreness at the injection site (temporary) 1 Week: A slight improvement in skin glow & hydration

An incisional pain model was used to establish experimental conditions, such as gingival incision in dental clinics