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These measures, reflecting muscle mass, functional strength and mobility have been combined to generate a primary composite score

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A synthetic growth-promoting plasma factor with wound healing activity

Mechanistically, stabilization of wild-type p53 and induction of the p53 target gene CDKN1A (p21) leads to decreased expression of the ribonucleotide reductase (RNR) subunits RRM1 and RRM2
