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The tissue becomes less vascularized, meaning less blood flow reaches the area to carry the medication into systemic circulation
As you get older, the systems that rely on NAD+ (like energy production, cognitive function, skin repair, immune health, and inflammation regulation) start to slow down, and declining NAD+ levels appear to be a key driver behind that slowdown
Deficiencies in vitamin B12 can significantly affect energy levels since it is responsible for red blood cell production and oxygen transport
