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For both targets, the assay was evaluated over a concentration range of 0.313 to 320 M and was demonstrated to have a quantitative dynamic range spanning nearly three orders of magnitude, with lower limits of quantification being 0.330 M for GSH and 0.370 M for cysteine

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Vitamin B12 deficiency results in megaloblastic anemia, GI lesions, and neurologic damage (which begins with an inability to produce myelin and is followed by gradual degeneration of the axon and nerve head)

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