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It may be prescribed in cases of confirmed biotin deficiency or certain medical conditions, and while it is sometimes used in hopes of improving hair or nail growth, its efficacy in otherwise healthy individuals remains unproven

10.1016/j.bbamcr.2009.09.017 203

Expert Opinion In contrast to the prior versions of this guideline, this update no longer divides treatments into first-line through sixth-line tiers

These are the types of studies that augment our approach to regenerative orthopedics
