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Parallel advances in clinical trial design, such as Bayesian and adaptive models, are also expected to improve patient stratification, accelerate recruitment, and optimize dosing regimens, ultimately increasing the efficiency of drug development pipelines 91
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Pereira, G
Hypoxia-inducible factor 1 (HIF-1) is an oxygen-sensitive transcription factor that plays a critical role in cellular survival and oxygen homeostasis under hypoxic conditions
