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Description
LL-37 is an antimicrobial peptide that forms part of the innate immune system
Kobayashi, S., Meir, A
While an updated meta-analysis of 32 randomized trials including 24,389 patients showed SDD was associated with lower mortality, it should be noted that the vast majority of positive trials were published well over a decade ago and are in settings with low antimicrobial resistance [327]
Clinical evidence from studies with NAC in depression is overall in line with preclinical findings and suggests a role of NAC as an adjunctive treatment to antidepressant therapy for symptom improvement
