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Description
Critical immune endpoints include (1): CD8+ T-cell infiltration density, assessed via immunohistochemistry for CD8 and Granzym (237) (2)

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First, other parameters of the inflammation process, OxS, antioxidant defence factors were not studied

Note that, although oxidative stress is accepted as a key modulator of the biological processes in neurodegenerative diseases [141], therapeutic interventions must also take into account the useful endogenous mechanisms regulated by ROS [142]