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Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions

Dena Dubals lab at UCSF (Cell Reports, 2017) showed that peripheral klotho fragment administration enhanced cognition and neural resilience in young, aging, and -synuclein transgenic mice through NMDA receptor-dependent mechanisms
This page covers both oral and subcutaneous research planning, the vial math for the common 20 mg vial, and the current safety and regulatory standing

10.1038/s41598-018-26956-7 87 LiuM.LiL.ChuJ.ZhuB.ZhangQ.YinX.et al (2015)
