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The degeneration and loss of motor neurons cause denervation at the neuromuscular junction that, in turn, lead to paralysis and death

[50] also found that ALA has an important antioxidant effect on brain dysfunction in rats, especially in the PFC and hippocampus, by decreasing myeloperoxidase (MPO) and NO activity, lipid and protein peroxidation, increasing antioxidant capacity and CAT activity and preventing cognitive dysfunction

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Sousa-Lima I., Fernandes A.B., Patarro R.S., Kim Y.B., Macedo M.P

Our study shows that the complete absence of food triggers a defensive response in CAT and elevates it to statistical significant levels