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The expiration date on the bottle is assigned by the manufacturer and is what you should follow if the bottle has not been opened

B12 & Autoimmune Disorders

Akaike, Protective effects of methylcobalamin, a vitamin B12 analog, against glutamate-induced neurotoxicity in retinal cell culture

Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise
