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M2 macrophages exhibit higher ferroportin levels, increased heme recycling, and robust glutathione synthesis, collectively establishing a ferroptosis-resistant environment that enables tumor progression and immune evasion

Additionally, low iodine intake is linked to an increased risk of thyroid cancer, and research suggests that correcting iodine deficiency can help protect against the development of more aggressive forms of thyroid cancer (47Trusted Source)

Chronic elevation at 12% significantly increases the risk of long-term microvascular complications , such as retinopathy, nephropathy, and neuropathy

Miyauchi et al
