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Description
biochemically, there is intracellular glutathione (GSH) depletion and decreased activity of glutathione peroxidase 4 (GPX4), lipid peroxides cannot be metabolized by the GPX4-catalyzed reduction reaction, and Fe 2+ oxidizes lipids in a Fenton-like manner, resulting in a large amount of ROS, which promotes ferroptosis 3,6
Purging typically resolves within four to six weeks
Always use sunscreen with a high SPF to protect your skin from UV rays and prevent the return of pigmentation
Laryngoscope investigative otolaryngology
