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Stiripentol, an anti-epileptic drug known to inhibit LDHA and to cross the bloodbrain barrier, was shown to lower H3K9la thereby enhancing the responsiveness of GBM cells to TMZ

Several other studies have also demonstrated increased oxidative stress [7,8,9,10,11,12]

In fact, MitoQ has been used in a range of in vivo studies, in rats and mice, and in two phase II human trials demonstrating that it can be safely delivered to patients with promising results, lending further support that mitochondria-targeted antioxidants may be applicable to a wide range of human pathologies that involve mitochondrial oxidative damage (Smith and Murphy, 2010)

Abstract Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of Cannabis sativa L