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Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease

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Categorical variables were expressed as frequency and analyzed by the chi-square or Fisher exact test (if more than 20% of the categories were expected to have a frequency less than 5)

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Moreover, the nhr-49(et7) gain of function mutation promoted thermotolerance, which required the conserved hsf-1 master regulator

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