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This seems to relate with the downregulation of genes related to ECM organization, TGF-, and MMP signaling in fibroblasts during the resolution phase of acute injuries whereas in chronic scenarios, these genes remain upregulated
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Its also why we caution patients strongly against treatment with Dermapen at spas and salons
Peptides can be combined in protocols: one peptide to reduce inflammation, another to recruit stem cells, and a third to boost matrix repair
