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Description
For anyone interested in longevity from a preserve organ function angle, the kidneys are usually one of the first places to start failing in older populations
Most disulfide-linked drugs are initially freed intact through proteolytic cleavage of the antibody and subsequently released as active metabolites via disulfide exchange or reduction by agents such as glutathione
An increased incidence of hepatocellular tumors was not seen at lower doses
Wu AH, McCay C, Broussard LA, et al
