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To better understand the ability of acyl chains to fit into the hydrophobic pore we modeled 3 separate ligands into the pore using PyRosetta 44 , palmitate, oleate, and lineolate (Fig

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As a constituent of topical anti-obese creams lipases are used in manufacturing of hair waving and also used for the curing of malignant tumors as digestive aids because lipases are initiate as activators of tumor necrosis factor (TNF) [131, 563]

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The peptides tolerability profile was described as indistinguishable from placebo in most safety assessments

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Lipid peroxidation at the membrane can disrupt the ion balance and increase membrane permeabilization [12]

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