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The molecular mechanism of such massive GSH transport and its connection to the other transport activities of MRP1 are unknown
Lack of insulin receptor signaling in Leprechaunism may result in the rare event of an alive but severely small for gestational age baby that will only survive if treated with recombinant-IGF-1 to substitute inulin receptor signaling with IGF1R signaling via their common intracellular pathways
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