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Most protocols recommend a 24 week break after a cycle to reassess progress and prevent diminishing returns

Suarez E P, Pugliese S, Galdiero E, Guida M, Libralato G, Saviano L, Spampinato M, Pappalardo C and Siciliano A 2023 Multigenerational test on Daphnia spp.: A vision and new perspectives

OHDSI is an open-science community which, through its central coordinating center at Columbia University, has established an international network of research and observational health databases

NHS guidance on vitamin B12 says theres not enough evidence to show what the effects may be of taking high doses of vitamin B12 supplements each day, and therefore you should not take more than has been advised by your doctor