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Promising in animals, limited in humans

The benefits of vitamin B12 in reducing histopathological changes of the adrenal gland can be observed where the adverse effects of PTU were reversed with improved capsule integrity, restoration of cortical cells with their regular cord-like arrangement in all cortical zones and medulla in addition to reducing the congestion, hemorrhage, and fatty degeneration

Older adults often produce less stomach acid, impairing B12 absorption from food
