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J Clin Med (2020) 9(4):941
[DOI] [PMC free article] [PubMed] [Google Scholar] Li H., Li Q.D., Wang P.Z., Wang M.S., Cui J., Diao T.Y., Li Q.H
Daily, consistent supplementation for at least 8 to 12 weeks is recommended for meaningful results
A single, intravenous or intranasal sub-anesthetic dose of ketamine, a non-competitive NMDA glutamate receptor channel blocker, produces a rapid onset of antidepressant response that can last several days in the majority of treatment resistant unipolar and bipolar depressed patients participating in a growing number of clinical trials 148150
