glutathione reductase human RCSB PDB It favors its accumulation in the regions of high electron flux in cells where reactive species are generated. Glutathione in Brain Disorders and
Description
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It is synthesized from three amino acids in two ATP-dependent steps, beginning with the formation of a peptide bond between -glutamate and cysteine by -glutamylcysteine synthetase (GSH1) and the subsequent addition of glycine, catalyzed by glutathione synthetase (GSH2) (Figure 1: GSH biosynthesis) [20]

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Munger K, Basile JR, Duensing S, Eichten A, Gonzalez SL, et al
