l-carnitine tmao nature medicine 2013 koeth Revisiting the Role of Carnitine in Heart Disease Through the Lens of the Gut Microbiota Frontiers | The gut microbial

PLoS ONE 11(12):e0165589 Nichols AR, Aris I, Rifas-Shiman SL, Hivert MF, Chavarro JE, Oken E (2025) History of pregnancy loss and risk for higher midlife blood pressure in parous females

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The possible underlying mechanism is associated with enhanced hepatic lipid oxidation via an Adenosine Monophosphate- Activated Protein Kinase- Acetyl-CoA carboxylase (AMPKAcetyl-CoA carboxylase) pathway, which leads to a reduction in liver fatty acid synthase activity, an increase in glycogen storage, and a decrease in tumor necrosis factor expression [157]