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Metabolic Flexibility and Acyl-CoA/CoA Ratio Disease states like kidney disease, fatty liver disease, insulin resistance and neurodegenerative diseases, myalgic encephalomyelitis/chronic fatigue syndrome, and fertility disorders may be linked to metabolic inflexibility caused by alterations in the carnitine cycle

The novelty of this study lies in the fact that we extracted and analyzed data from studies of patients with chronic liver disease and elevated liver enzyme levels