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While there is substantial variation, 1000 mg/d of NAC will substantially increase glutathione in virtually all patients.30 For the rare patient who reacts to NAC, SAMe can be used.31 Do not use methionine as it will increase homocysteine

These strategies may include antioxidant supplementation, pharmacological agents with antioxidant properties (e.g., statins), and strict inflammation control

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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Wu M., Huang S
