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& Rothstein, R
Sluss PM, Hayes FJ, Adams JM, et al
Critically, the integrity of this initial pulmonary barrier can be compromised by inhaled toxic substances (e.g., PM., O, cigarette smoke), which downregulate tight junction proteins and increase epithelial permeability
The embryonic origin of pericytes in tissues also comprise another difference, since CNS pericytes grow from the neural crest whereas the mesoderm is the origin of other tissue pericytes ( It is also vital to highlight the microglia, which are resident macrophages in the neurological system
