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Cells were cultured with or without supplementation of riboflavin (0.4 mg/L) or FAD (10 M) or were treated with increasing lumiflavin concentrations
A segmental nevus spilus may indicate the presence of RASopathy (a heterogeneous group of genetic diseases with the common denominator of a mutation in the RAS/mitogen activated protein kinase signaling pathway) [44]
In fact, this link is so compelling that many researchers have referred to Alzheimer disease as type 3 diabetes (Ahmed 2015
