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Furthermore, compared to the CON group, there are 58 commonly upregulated and 105 commonly downregulated differential metabolites in both the WKY and ESC groups, exhibiting the same trend of changes in these groups (Fig

3 Results 3.1 Nitazoxanide improved liver function in rats with MTX-hepatotoxicity As depicted in Figure 2, an impaired liver function was observed in the MTX group compared to CTRL, as indicated by significantly elevated serum liver enzymes

Long-term Longitudinal Studies: Most existing human data are derived from short-term interventions

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