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M.Dejesus-HernandezM.et al

With aging and chronic exposure to oxidative stress, bioenergetic efficiency declines, leading to a reduced regenerative capacity and promoting inflammation

GSTP1 expression may predict the pathological response to 5-fluorouracil/epirubicin/cyclophosphamide in estrogen receptor (ER)-negative tumors (80)

And so if the purpose of sleep is to restore the energy that you used up, but then you intervene by putting creatine in there, now you can keep that energy going and you can go more hours before you need to get rest and restore that energy, because youve increased your capacity to distribute it
