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75 Conversely, forced overexpression of CDO1 in breast cancer cells shifted the flux from glutathione synthesis towards cysteine catabolism, consequently increasing ROS levels and leading to reduced cell viability and growth

Specifically the disorder referred to as progressive external ophthalmoplegia with mitochondrial deletions, autosomal dominant 3 (PEOA3) results from mutations in the TWNK gene

Indeed, there is evidence of mechanistic heterogeneity in the function of zinc transporters across different subtypes of BC
