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Fluid percussion injury in 1- to 3-day-old piglets showed greater reductions in CBF than did the same injury in juvenile (3- to 4-week-old) pigs (Armstead, 1999)
While glutathione, a strong antioxidant, boosts radiance, supports skin repair, and protects against free-radical damage

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Future research should prioritize longitudinal trials to delineate the causal roles of specific inflammatory pathways (e.g., TNF-, IL-6) and their therapeutic modulation across all CKD stages
