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Lipolysis can be locally sensed in white fat by afferent nerves to trigger a neural circuit from WAT to BAT that acutely induces BAT thermogenesis, mediated by representative FAs eicosopentanoic acid and arachidonic acid (154)

Dehydration and electrolyte imbalances, which can occur secondary to reduced food and fluid intake or gastrointestinal side effects such as nausea and vomiting, may also contribute to these sensations

It is located around 3650 meters above sea level on the southwest of Bolivia, which is in the Andes Mountains