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Health Canada (EC 2010) uses the same approach to evaluate potential risks resulting from dermal exposure to 1,4-dioxane
To do so, Ishikawa cells were surface biotinylated and lysed, and then lysates were incubated with z13 peptide-conjugated agarose beads

The approval is a long time coming for ImmunityBio after the FDA rejected Anktivas Biologics License Application in May 2023 due to issues with a pre-license inspection of a third-party manufacturer

Early growth response-1 in cardiovascular pathobiology
