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The drug interactions that are of clinical significance are anticonvulsants, statins, macrolide antibiotics, triazole antifungals, digoxin, antiarrhythmics, and others
[DOI] [PMC free article] [PubMed] [Google Scholar] Liu J., Head E., Kuratsune H., Cotman C.W., Ames B.N

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Insulin receptor signaling in normal and insulin-resistant states