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In lung cancer cells, miR-155-5p was found to downregulate the transcription factor FOXO3a, leading in turn to downregulation of IGFBP-1

doi: 10.1093/cid/ciad348 53 YoussefJGZahiruddinFYoussefGPadmanabhanSEnsorJPingaliSRet al

Transforming growth factor beta suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model

The main mechanism of regulated cell death involves organisms coordinating the elimination of damaged cells at risk of tumor transformation or cells hijacked by microorganisms for pathogen replication
