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Chugging beer, shots etc., does not get you drunk immediately because your body still needs time to absorb the alcohol but when it does hit you it hits you ALL at once = intoxicated faster

Effective preventative measures for patients at risk for cholelithiasis include a slower rate of weight loss, increasing/including some dietary fat in the diet (assuming the patient has been on a very low-calorie diet containing little or no fat), or administration of ursodeoxycholic acid