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In a randomized controlled trial, low-dose aspirin improves endothelial cell health in psoriasis via platelet cyclooxygenase-1 (COX-1) inhibition, which reduces the downstream release of membrane-bound arachidonic acid and TxB2(the inactive metabolite of TxA2) (52)
Gal-3 has antiapoptotic effects, unlike most members of the galectin family (91)
AppletonRJonesAGambleCWilliamsonPWiggsLMontgomeryPet al
