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Description
In addition to cell-intrinsic exhaustion programs, the successful infiltration of activated T cells into the tumor bed is a dynamic, multistep process that can be conceptualized as a two-stage activation cascade

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The first discovered function of Grx3 was related to that of protein kinase C theta, and in T-cells, Grx3 colocalizes with it, hence the name PICOT [157]

American Journal of Therapeutics
