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In tumor therapy, cellular senescence is not only a common nonlethal cellular endpoint after IR induction, but also its dual roles in radiotherapy have triggered an increasing interest

Clinical trials in diabetics have documented the nutritional safety and benefits of alpha-lipoic acid for aiding blood sugar metabolism

developed a polyethylene glycolized single-atom iron-containing nanocatalyst, which can disperse iron atoms into carbon nanomaterials, and modified polyethylene glycol on the surface of nanoparticles, so that H 2 O 2 can be easily absorbed and dissociated by amorphous iron, and polyethylene glycolized single-atom iron-containing nanocatalysts can initiate the Fenton reaction under the acidic microenvironment of tumors and single-atom nanocatalysts are well biodegraded and biocompatible without any significant toxic reactions [157]