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In this context, for instance, the pharmacokinetic profile needs to be defined in detail, including the type of metabolic enzymes involved in its degradation, interactions resulting from the binding of the drug to plasma proteins, etc

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(2001).Insulin and insulin-like growth factor I receptors: Similarities and differences in signal transduction
The solution should be kept at refrigerator temperature between 2 and 8 degrees Celsius at all times