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With its ability to promote sustainable weight loss, semaglutide has gained immense popularity with its commercial alternatives, such as Wegovy and Ozempic

B12 deficiency upregulates lipogenesis in mature human WAT To validate the evidence of low B12 effect on lipogenesis in the Chub-S7 cells and primary Sc adipocytes, gene expression was further investigated in ScWAT and OmWAT derived from pregnant women with sufficient and deficient levels of B12

While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables