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First, gastrointestinal distress: tirzepatide's most common side effects are nausea (up to 31% of patients in SURPASS trials), vomiting, diarrhea, and decreased appetite
Consistent with the importance of SYT1 for synaptic transmission, we found that SYT1 colocalized with Bassoon at 97% of spines, and SYT1 clusters co-distributed with Bassoon and PSD-95 nanomodules at synapses (Fig

doi: 10.1016/j.cell.2007.11.019 3 VerhoeffKHenschkeSJMarfil-GarzaBADadheechNShapiroAMJ

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