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For example, homocysteine-induced endoplasmic reticulum protein, which is located in the ER membrane of neurons and astrocytes in the Central Nervous System (SNC), is found accumulated in Lewy bodies, suggesting a role in their formation and further development of PD [117]

Additional in vitro studies indicate the formation of hydroxylated derivatives of STG, as well as N -acetyl-cysteine adducts of formed hydroxyquinones in humans (Pfeiffer et al

ROS have been implicated in a number of pathologic processes, including reperfusion injury, cancer, inflammatory disease, and aging

Diabetes 2011;60:27109
