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Description
Elevated concentrations of free radicals in the central nervous system (CNS) significantly influence the pathophysiology and progression of neurodegenerative and inflammatory processes [1]

milder cognitive effects include various neurodevelopmental deficits, including intellectual impairment (66, 67)

The heterogeneity of delta 4-3-ketosteroid reductase (5) J Biol Chem

The Grx-SG intermediate is cleaved by a GSH molecule, resulting in reduced Grx and GSSG, which is subsequently reduced by GR [150] (Figure 3)
