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Furthermore, the striatal injection of an adeno-associated virus (AAV)-mediated VEGF expression provided neuroprotection and behavioral improvement in rats treated with 6-OHDA [133]
Zinc supplementation induces CD4+CD25+Foxp3+ antigen-specific regulatory T cells and suppresses IFN-gamma production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1

The endoplasmic reticulum also has tight restriction on exchange with the cytosol and it, uniquely, maintains an oxidizing redox status to support protein folding and disulfide formation

- blockade of factor translocation from the cytoplasm to nucleus [88,89]
