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The authors noted that poor or intermediate metabolizers demonstrate reduced drug clearance, which can elevate systemic exposure and increase ADR risk, whereas rapid or ultrarapid metabolizers may experience subtherapeutic exposure and treatment failure

This remains challenging because anti-TB drugs such as rifampicin induce cytochrome P450 enzymes

The full coverage of the skin envelope improved the soft tissue support of the entire operated breast without needing a specific post-operative garment, thereby reducing edema and seroma formation 15 ) while also improving pain control
