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Because TrxR1 and hTrx1 are present in human serum and they appear in high-molecular-weight complexes (Figure 5B, serum TrxR1 appeared mainly in high-molecular-weight complexes (between 130-170 kDa) when analyzed by non-reducing SDS-PAGE followed by Western blotting

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J Biol Chem 276: 2193821942 Mbaya E, Oules B, Caspersen C, Tacine R, Massinet H, Pennuto M, Chretien D, Munnich A, Rotig A, Rizzuto R, Rutter GA, PaterliniBrechot P, Chami M (2010) Calcium signallingdependent mitochondrial dysfunction and bioenergetics regulation in respiratory chain Complex II deficiency

[DOI] [PubMed] [Google Scholar] 324.Nagarajan S., Chellappan D.R., Chinnaswamy P., Thulasingam S