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Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R

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Severe B12 deficiency triggers cascading metabolic dysfunction

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Methionine synthase: Converts homocysteine to methionine (with folate)

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