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As such, we believe that there is a need for more detailed studies outlining the diverse biological functions of GST, in order to assist drug discovery and unlock more exciting possibilities in the realm of tumor treatments

Specifically, images were first converted to greyscale and then Gaussian blurred to fill breaks in the organoid edges, and the edges were detected by a Canny edge filter

HMGB1 belongs to DAMPs and is one of the key elements for tumor cell immunogenicity, as it will bind to its receptor and activate the immune system once it is released outside of cell (89)